From the WSJ:
Scientists don’t yet understand who will benefit from a particular antidepressant, or any antidepressant at all, beyond a placebo effect of taking a pill. Only 15% of people with major depression experienced a substantial benefit from taking antidepressants beyond the placebo effect, according to a 2022 study.
HHS will encourage doctors to consider lifestyle changes, over drugs, for depression.
Civil Twilight 